Anti-PMCA 抗体

Catalog Number :RS-6328R

Quantity size :   0.1ml  （dilute with pH 7.4    0.01 M PBS or antibody diluent ） Background: Annexin V （ANX5） is a member of a family of calcium-dependent phospholipid binding proteins.

This family of annexins also includes giardin that has been shown to function as an annexin; pfam00191
Plasma membrane-type Ca2+-ATPases （PMCAs） mediate the export of bivalent calcium ions from eukaryotic cells. As members of the P class of ion-motive ATPases, PMCAs are a functionally diverse group of proteins that are derived from alternatively spliced transcripts originating from at least four distinct genes. The expressiAnti-PMCA 抗体PMCA 抗体on of different PMCA isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, and with respect to the physiological needs of specific cell and tissue types. Spatial and temporal rates of resting intracellular Ca2+ concentrations and Ca2+ signaling in eukaryotic cells are dependent on the array of PMCA isoforms that are expressed in concert with the rate of Ca2+ export.

Specificity : Anti-PMCA a rabbit polyclonal antibody             

specific for PMCA of  Human,Mouse,Rat,Pig

• use for western blotting,elisa,immunoprecipitation and immunohistochemistry
• Protein G affinity chromatography purification, purity :>95%
• Isotype:  IgG
• mol wt:  130kDa

Application :  

•   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500
• not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user..

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃Anti-PMCA 抗体PMCA 抗体

Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.